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Posts Tagged ‘obesity’

always hungry leptin resistance

You would think people who are overweight or obese would never feel hungry—after all, they have all that extra fat to burn. But in a cruel twist of metabolic trickery, carrying excess fat can actually make you hungrier thanks to a phenomenon called leptin resistance.

What is leptin?

Leptin is a “satiety” hormone secreted by fat cells that tells the brain when you have had enough to eat. Eating causes the secretion of leptin, which signals that the stomach is full and it’s time to stop eating. Between meals or during long periods without food, leptin levels drop, triggering hunger and motivating you to eat and replenish the body’s energy stores.

Leptin resistance causes you to always feel hungry

Because fat cells secrete leptin, overweight and obese people should never feel hungry. Unfortunately, the reverse happens. Excess fat secretes too much leptin, bombarding leptin receptors on cells. Eventually these cells become overwhelmed and shut down their leptin receptors to protect themselves. This is called leptin resistance—leptin can no longer get into the cells to deliver their message that the stomach is full and it’s time to stop eating.

Hence the leptin-resistant person always feels hungry and is prone to overeat, even if she or he is carrying plenty of fat. In addition to causing chronic hunger, leptin resistance doubly vexes the overweight person by promoting fat storage and making it tough to lose weight.

Leptin serves other roles beyond hunger and satiety. It is also important for fertility, libido, and puberty. Leptin resistance could explain why obese girls are 80 percent more likely to start puberty earlier than girls of normal weight.

High triglycerides block leptin

High triglycerides have been shown to block leptin. Diets high in alcohol, sugars and carbohydrate-rich foods, such as breads, pasta, rice, and potatoes, raise triglycerides considerably. High triglycerides have been shown to block the ability of leptin to pass into the brain to tell it you’re full.

Diet can reverse leptin resistance and chronic hunger

The key to unwinding leptin resistance is to adopt a diet that will restore leptin sensitivity. The eating habits that typically lead to being overweight or obese—overeating and eating too many sweets and starchy foods, processed foods, and foods fried in industrialized fats—also lead to leptin resistance, high triglycerides, and hence the feeling of always being hungry.

To restore leptin sensitivity, diminish chronic hunger, and release excess fat, consider the following leptin facts and begin making the changes you need to your own diet and lifestyle.

  • Regular exercise, particularly strength training and interval training, lowers leptin.
  • Sugar, corn syrup, and high fructose corn syrup found in sweets and sodas make the brain resistant to leptin. Sweets also raise triglycerides so leptin can’t reach the brain.
  • Healthy fats activate leptin’s satiety switch. Eat coconut oil, butter, ghee, olive oil, avocado, salmon, etc. as part of a lower-carb diet.
  • Omega-3 fatty acids regulate leptin sensitivity. Ask your practitioner whether a fish or krill oil supplement may help you.
  • Overeating causes leptin resistance. Ditch the sodas, sweets, processed foods, and high-carbohydrate foods, which trigger cravings in many people. Healthy fats and sufficient protein curb cravings. Consider hypnotherapy, acupuncture, or other tools to address an eating disorder that may cause you to overeat.

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sitting-disease

Do you eat a healthy diet and exercise regularly but sit long hours each day at work? If so, you could be undoing all your good work.

Sitting, even if you otherwise practice healthy habits, is associated with poor cardiovascular health, higher inflammation, and more belly fat, according to a 2011 Australian study. This is bad news for the millions of Americans who must work at a desk. In fact, it can feel downright insulting to learn that all our healthful efforts are being thwarted by our jobs.

Studies link prolonged sitting with compromised metabolic health, higher risk of disease, and shorter life span. Witness this cascade of ill effects:

  • Electrical activity in muscles goes silent
  • Calorie burning plummets
  • Insulin sensitivity drops, raising the risk of obesity and Type 2 diabetes
  • Enzymes responsible for clearing fat and triglycerides from the bloodstream plunge, lowering the levels of HDL (good) cholesterol

Sadly, these risks remain regardless of our physical activity level outside of work. Worst of all, these metabolic changes don’t happen gradually, but instead swiftly, within 24 hours.

Antidotes to sitting long hours

The results of your good exercise and diet habits needn’t be lost to your office chair. Sitting disease antidotes can be as simple as moving around more or working while standing.

Create a treadmill desk

A treadmill desk is just what it sounds like, a desktop built over a treadmill. Users walk very slowly on the treadmill and can easily talk, type, and perform other desk work while burning 100 calories an hour and staving off metabolic risks. Treadmill desks can be homemade, purchased to fit over an existing treadmill, or ordered, all inclusive, for up to $4,400.

Stand at your desk

A quicker and less cumbersome fix is a standing desk. To make one, try stacking something tall on your desk on which to set your computer. If you work at home, you might choose to work on your laptop while standing at the kitchen counter. Standing burns more calories than sitting and engages more muscles, enhancing metabolic activity.

Frequent breaks are key

If you do choose to sit, you can mitigate the effects of sitting disease with frequent breaks and lots of movement throughout the day. Australian researchers found those who took frequent breaks had lower levels of C-reactive protein, an important marker of inflammation, and smaller waists as well. Waist size, like excess belly fat, is a marker for increased risk for heart disease, Alzheimer’s, and other inflammation-related disorders. High-risk waist circumference is over 40 inches for men and over 35 inches for women.

Take a stand against excessive sitting. Get up every half hour. Move about in your chair. Take the stairs instead of the elevator. Park at the outer reaches of the parking lot. Go ahead and fidget and bustle, and trot between the computer and the printer, or to the bathroom. Research shows not only will you combat sitting disease, but you’ll also be less likely to gain weight compared to your more sedentary coworkers.

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